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. 2020 Oct 31;56:58–68. doi: 10.1540/jsmr.56.58

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©2020 The Japan Society of Smooth Muscle Research

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3. — Whole mount preparations of W^sh/W^sh mice musculatures.

ICC were detected to have TMEM16A immunoreactivity in the gastrointestinal musculature. In the gastric corpus (A), ICC-MY (arrows) were observed to have multipolar shape in the myenteric layer. In the gastric antrum (B), ICC-MY (arrows) showed a multipolar shape and existed under crowded circumstances in the myenteric layer. In the small intestine (C), ICC-DMP (arrowheads) in the circular muscle layer were observed to have a bipolar, slender shape. In the cecum (D), ICC-MY (arrows) were multipolar-shaped. In the colon (E, F), ICC-SM (double arrowheads, E) and ICC-MY (arrows, F) were observed in the submucosal layer of the circular muscle and myenteric layer, respectively. Bar: 100 μm.