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. 2020 Oct 31;56:58–68. doi: 10.1540/jsmr.56.58

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©2020 The Japan Society of Smooth Muscle Research

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4. — ICC and FLC in BALB/c and W^sh/W^sh mice.

ICC and FLC were detected to have TMEM16A (green) and PDGFRα (red) immunoreactivities, respectively. In the stomach (A, B), small intestine (C, D), and proximal colon (E, F), ICC were observed only as restricted subtypes in W^sh/W^sh mice (B, D, F), whereas FLC were observed as being similar to that in BALB/c mice (A, C, E). ICC-DMP (arrowheads), ICC-SM (double arrowheads), and ICC-MY (arrows) were observed in W^sh/W^sh mice tissues. c and l represent circular and longitudinal muscle layers, respectively. Asterisks show myenteric layer. Bar: 50 μm.