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Cross-reactive B cell epitopes tagging SARS-CoV-2 Spike protein. Panel shows a surface rendering of the tertiary structure of the trimeric SARS-CoV-2 Spike protein in the open state with cross-reactive B cell epitopes in red. The Spike RBD is shown in green and in blue ACE2. We show the location and sequence of three B cell epitopes that are in RBD or nearby. These B cell epitopes can be the targets of neutralizing antibodies.
