Table 2.

Effects of Ex and tempol on the SBP and biochemical variables in SHR.

	Control (n = 10)	Ex (n = 10)	Tmp (n = 10)	Ex + Tmp (n = 10)
SBP (mmHg)	225 ± 6	211 ± 4∗∗	212 ± 6∗∗	202 ± 4∗∗#+
DBP (mmHg)	130 ± 5	122 ± 5	125 ± 3	123 ± 3
Body weight (g)	386 ± 15	350 ± 23	366 ± 13	358 ± 19
Kidney weight/body weight (g/kg)	6.48 ± 0.27	5.93 ± 0.19	6.04 ± 0.29	6.12 ± 0.11
Total cholesterol (mg/dl)	64.40 ± 2.08	61.80 ± 2.35	59.20 ± 2.11	59.00 ± 2.25
Triglyceride (mg/dl)	53.00 ± 4.39	61.40 ± 4.66	51.80 ± 5.75	61.20 ± 5.04
Free fatty acid (mEq/l)	0.21 ± 0.01	0.20 ± 0.02	0.20 ± 0.02	0.18 ± 0.02
Glucose (mg/dl)	199.80 ± 5.62	187.80 ± 5.85	187.00 ± 7.50	193.40 ± 4.12
Plasma creatinine (mg/dl)	0.17 ± 0.01	0.11 ± 0.02∗∗	0.14 ± 0.02	0.08 ± 0.01∗∗+
Creatinine clearance (ml/min)	2.50 ± 0.51	4.57 ± 0.67∗∗	3.28 ± 0.46	5.82 ± 0.75∗∗+
Plasma urea nitrogen (mg/dl)	17.86 ± 0.60	17.34 ± 0.75	17.28 ± 0.73	16.78 ± 0.79

Values are means ± SEM. ^∗P < 0.05 vs. the control group. ^∗∗P < 0.01 vs. the control group. ^#P < 0.05 vs. the Ex group. ⁺P < 0.05 vs. the Tmp group.