Table 1.
Demographics and clinical data of hospitalized children with single HAdV-3 or single HAdV-7 infection.
| Characteristic | All patients (N = 73) | ||
|---|---|---|---|
| HAdV-3 (N = 36) | HAdV-7 (N = 37) | P | |
| Male sex | 25 (69.4) | 29 (78.4) | 0.463 |
| Median age, month (range) | 33.1 (6.7-92.5) | 25.2 (3.2-111) | 0.201 |
| Fever duration days (range) | 6.6 (1-21) | 11.1 (2-34) | 0.002 |
| Median peak temperature, °C | 39.8 ± 0.8 | 39.7 ± 0.5 | 0.796 |
| Respiratory symptoms | |||
| Cough | 29 (80.6) | 32 (86.5) | 0.494 |
| Rhinorrhea | 11 (30.6) | 7 (18.9) | 0.249 |
| Tachypnea/dyspnea | 10 (27.8) | 21 (72.4) | 0.012 |
| Pleural effusion | 1 (2.8) | 16 (43.2) | <0.001 |
| Rales | 19 (52.8) | 31 (83.8) | 0.004 |
| Laboratory tests | |||
| WBC, ×109 cells/l | 13.7 ± 6.3 | 8.9 ± 4.4 | <0.001 |
| >15 × 109 cells/l | 12 (33.3) | 5 (13.5) | 0.045 |
| CRP, mg/l (IQR) | 32.8 (54.7–5.1) | 34.6 (59.6–8.1) | 0.839 |
| >0.15 mg/l | 35 (97.2) | 37 (100) | 0.307 |
| >40 mg/l | 10 (27.8) | 11 (29.7) | 0.854 |
| PCT, ng/ml (IQR) | 0.74 (0.70-0.11) | 3.34 (3.95–0.34) | <0.001 |
| >0.05 ng/ml | 32 (88.9) | 36 (97.3) | 0.199 |
| >0.5 ng/ml | 10 (27.8) | 27 (72.9) | <0.001 |
| Outcomes | |||
| Hospitalized duration days (range) | 10.7 (3-44) | 17.7 (3-84) | 0.01 |
| Intensive care required | 19 (52.8) | 23 (62.2) | 0.417 |
| Mechanical ventilation | 4 (11.1) | 11 (29.7) | 0.049 |
| Death | None | 4 (10.8) | <0.001 |
Values are no. (%) of patients or mean ± SD, unless otherwise indicated. Range: extreme values at both ends; IQR: interquartile range; WBC: whole blood cell; CRP: C-reactive protein; PCT: procalcitonin.