Table 2.
Demographics and clinical features of hospitalized children with adenovirus infection.
| Characteristic | All patients (N = 84) | ||
|---|---|---|---|
| Nonsevere infection (N = 56) | Severe infection (N = 28) | P | |
| Male sex | 40 (71.4) | 20 (71.4) | 1.00 |
| Median age, month (range) | 33.7 (4.8-111) | 16.1 (3.2-58.7) | 0.001 |
| Fever duration days (range) | 6.7 (1-21) | 12.9 (3-34) | <0.001 |
| Median peak temperature, °C | 39.7 ± 0.7 | 39.9 ± 0.5 | 0.175 |
| Respiratory symptoms | |||
| Cough | 43 (76.8) | 26 (92.8) | 0.07 |
| Rhinorrhea | 18 (32.1) | 5 (17.8) | 0.166 |
| Tachypnea/dyspnea | 12 (21.4) | 22 (78.6) | <0.001 |
| Pleural effusion | 3 (5.3) | 15 (53.6) | <0.001 |
| Rales | 29 (51.8) | 28 (100) | <0.001 |
| Laboratory tests | |||
| WBC, ×109 cells/l | 12.4 ± 6.4 | 10.8 ± 6.5 | 0.307 |
| >15 × 109 cells/l | 15 (26.8) | 6 (21.4) | 0.593 |
| CRP, mg/l (IQR) | 29 (44.3–4.6) | 47.9 (63-18) | 0.032 |
| >0.15 mg/l | 54 (96.4) | 28 (100) | 0.311 |
| >40 mg/l | 14 (25) | 12 (42.8) | 0.095 |
| PCT, ng/ml (IQR) | 0.77 (0.72–0.11) | 4.39 (4.07–0.87) | <0.001 |
| >0.05 ng/ml | 51 (91.1) | 27 (96.4) | 0.658 |
| >0.5 ng/ml | 18 (32.2) | 24 (85.7) | <0.001 |
| Outcomes | |||
| Hospitalized duration days (range) | 10.2 (3 - 36) | 20.2 (3 - 84) | <0.001 |
| Intensive care required | 21 (37.5) | 26 (92.8) | <0.001 |
| Mechanical ventilation | None | 15 (53.6) | <0.001 |
| Death | None | 4 (14.3) | <0.001 |
Values are no. (%) of patients or mean ± SD, unless otherwise indicated. Range: extreme values at both ends; IQR: interquartile range; WBC: whole blood cell; CRP: C-reactive protein; PCT: procalcitonin.