Table 2.

Number of patients with adverse events.

Adverse events	Melissa officinalis extract group (n = 12)	Placebo group (n = 11)
Bruising	1	0
Headache	1	0
Hematuria	1	0
Upper respiratory infection	1	2
ALT elevation	0	1*
AST elevation	0	1*
Hyperkalemia	0	1
Hypokalemia	0	1
Rash maculopapular	0	2 (1*)
Weight loss	0	1

ALT alanine aminotransferase; AST aspartate aminotransferase.

*Adverse events were reported during the extension period.