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. 2020 Oct 16;7:583523. doi: 10.3389/fmolb.2020.583523

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Copyright © 2020 Rath and Kumar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Temperature sensitivity of the S1 domain of Spike protein. RMSDs of Spike glycoprotein (A) S1 and (B) S2 domain showing stability of the S2 chains. The differential fluctuations of chains (C) A, (D) B, (E) C, and the average RMSD of the three chains (F) of S1 domain at 10°C (black), 20°C (red), 30°C (green), 40°C (blue), and 50°C (magenta) implying effect of temperature of the chain stability.