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. 2020 Oct 16;7:583523. doi: 10.3389/fmolb.2020.583523

FIGURE 5.

FIGURE 5

Structures of the receptor binding domain of Spike protein after 200 ns of simulation at different temperatures exhibit diverse structural dynamics. Time-averaged conformations of RBD of SARS-CoV-2 Spike protein at, (A) 10°C, (B) 20°C, (C) 30°C, (D) 40°C, and (E) 50°C. The three chains are colored in lime, cyan, and orange. The receptor binding motif (shown in magenta) is oriented in a confined conformation at higher temperatures.