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. 2020 Oct 30;31(5):2726–2736. doi: 10.1007/s00330-020-07271-0

Table 4.

Laboratory data, lung volumes, and CT score in patients underwent CPAP and invasive ventilation by ET. Statically significant differences are highlighted in italic

N = 108 CPAP ET
Yes No p value Yes No p value
Age (years old ± SD) 66 ± 11 63 ± 10 0.339 63 ± 7 65 ± 11 0.674
Sex male (n; %) 29; 26.85 42; 38.88 0.454 22; 20.37 49; 45.37 0.088
WBC (× 103/mm3 ± SD) 7.35 ± 3.30 8.75 ± 5.54 0.286 10.72 ± 3.55 7.26 ± 3.55 0.002
Neutrophils (× 103/mm3 ± SD) 5.49 ± 2.76 5.81 ± 3.35 0.764 7.36 ± 3.44 5.18 ± 2.83 0.005
Lymphocytes (× 103/mm3 ± SD) 1.26 ± 0.91 1.47 ± 1.78 0.815 1.30 ± 0.86 1.40 ± 1.59 0.708
PLT (× 103/mm3 ± SD) 222.54 ± 111.56 246.50 ± 115.36 0.325 270.72 ± 113.88 224.56 ± 112.14 0.062
CRP (mg/l ± SD) 7.47 ± 6.99 7.88 ± 8.64 0.953 9.87 ± 11.37 6.93 ± 6.25 0.768
SaO2 (%, median, range) 93 (89–94) 95 (92–99) 0.037 95 (91–98) 94 (91–96) 0.081
PaO2 (mmHg ± SD) 40.34 ± 96.64 85.48 ± 26.46 0.507 87.62 ± 23.33 91.01 ± 36.32 0.436
PaCO2 (mmHg ± SD) 38.85 ± 5.67 37.24 ± 7.82 0.266 39.91 ± 10.05 34.85 ± 5.67 0.029
pH (± SD) 7.44 ± 0.05 7.38 ± 0.42 0.769 7.42 ± 0.37 7.40 ± 0.55 0.384
HCO3 (mEq/l ± SD) 24.40 ± 4.12 26.30 ± 4.31 0.383 27.80 ± 4.95 24.59 ± 3.70 0.010
P/F ratio ± SD 206.97 ± 84.67 247.39 ± 110.12 0.080 185.63 ± 92.28 248.12 ± 100.88 0.007
VLV (ml, mean ± SD) 2524.16 ± 1276.04 2795.57 ± 1294.35 0.245 2326.00 ± 1076.47 2820.52 ± 1338.98 0.176
TLV (ml, mean ± SD) 3834.72 ± 1219.99 3894.16 ± 1216.32 0.672 3882.68 ± 1118.17 3865.67 ± 1251.95 0.815
CONS-V (ml, mean ± SD) 337.54 ± 267.01 292.67 ± 350.59 0.057 472.32 ± 411.29 251.10 ± 256.77 0.024
GGO-V (ml, mean ± SD) 972.83 ± 466.38 804.25 ± 385.32 0.107 1085.36 ± 376.29 792.63 ± 417.26 < 0.001
GGO-V/TLV (%, median, range) 22.10 (2.79–61.50) 26.97 (3.44–67.80) 0.160 28.81 (3.80–49.9) 18.97 (2.84–59.9) 0.001
CONS-V/TLV (%, median, range) 7.49 (3.12–38.8) 4.96 (0–35.5) 0.127 11.61 (11.54–27.48) 5.08 (16.54–47.59) 0.033
GGO-V/VLV (%, median, range) 31.40 (3.25–110.44) 28.72 (6.78–298.41) 0.172 48.52 (29.8–377.04) 26.24 (18.91–198.0) 0.001
CONS-V/VLV (%, median, range) 11.29 (1.12–22.43) 6.68 (0–11.54) 0.740 19.66 (31.41–314.43) 7.13 (1.11–198.31) 0.041
VLV/TLV (%, median, range) 70.48 (12.91–45.60) 74.38 (39.65–99.01) 0.132 59.04 (11.32–70.84) 75.82 (70.11–94.14) 0.002
CONS-V + GGO-V/TLV (%, median, range) 29.52 (5.86–44.30) 25.62 (7.98–54.31) 0.131 40.96 (38.53–86.09) 24.18 (17.67–30.01) 0.001
CT score (median, range) 27 (20–31) 22 (16–29) 0.370 30 (10–35) 21 (7–23) 0.035