Table 2.
Characteristics | Propensity 1:2 Matching (n = 246) | IPTW (n = 540) | ||||
---|---|---|---|---|---|---|
Preoperative CRT (n = 82) | Postoperative CRT (n = 164) | P value | Preoperative CRT (n = 73) | Postoperative CRT (n = 467) | P value | |
Sex | 0.521 | 0.366 | ||||
Male | 55 (66.3%) | 118 (72.0%) | 54 (73.5%) | 321 (68.7%) | ||
Female | 27 (32.9%) | 46 (28.0%) | 19 (26.5%) | 146 (31.3%) | ||
Age (years) | ||||||
Mean (SD) | 57.3 (10.9) | 57.2 (8.0) | 0.964 | 52.9 (11.8) | 53.5 (10.5) | 0.654 |
Primary location | 0.994 | 0.334 | ||||
Upper 1/3 | 26 (31.7%) | 52 (31.7%) | 26 (36.0%) | 130 (27.8%) | ||
Middle 1/3 | 24 (29.3%) | 49 (29.9%) | 19 (25.5%) | 152 (32.5%) | ||
Lower 1/3 | 32 (39.0%) | 63 (38.4%) | 28 (38.5%) | 185 (39.7%) | ||
T stage at diagnosis | 0.266 | 0.070 | ||||
T3 | 5 (6.1%) | 19 (11.6%) | 15 (20.3%) | 144 (30.8%) | ||
T4a | 60 (73.2%) | 120 (73.2%) | 54 (73.3%) | 275 (58.9%) | ||
T4b | 17 (20.7%) | 25 (15.2%) | 5 (6.3%) | 48 (10.2%) | ||
N stage at diagnosis | 0.295 | 0.118 | ||||
N0 | 1 (1.2%) | 2 (1.2%) | 1 (1.0%) | 3 (0.7%) | ||
N1 | 19 (23.2%) | 42 (25.6%) | 9 (12.7%) | 88 (18.9%) | ||
N2 | 34 (41.5%) | 60 (36.6%) | 27 (37.3%) | 149 (32.0%) | ||
N3a | 26 (31.7%) | 44 (26.8%) | 32 (44.0%) | 161 (34.6%) | ||
N3b | 2 (2.4%) | 16 (9.8%) | 4 (5.1%) | 64 (13.8%) | ||
Lymphadenectomy | 0.625 | 0.121 | ||||
D0/D1 | 8 (9.8%) | 21 (12.8%) | 5 (7.1%) | 62 (13.3%) | ||
D2 | 74 (90.2%) | 143 (87.2%) | 68 (92.9%) | 405 (86.7%) |
IPTW, inverse probability of treatment weight; CRT, chemoradiotherapy.