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. 2020 Oct 16;10:560115. doi: 10.3389/fonc.2020.560115

Table 2.

Baseline demographic and clinical characteristics of patients in the propensity score-matched cohort and inverse probability of treatment-weighted cohort.

Characteristics Propensity 1:2 Matching (n = 246) IPTW (n = 540)
Preoperative CRT (n = 82) Postoperative CRT (n = 164) P value Preoperative CRT (n = 73) Postoperative CRT (n = 467) P value
Sex 0.521 0.366
Male 55 (66.3%) 118 (72.0%) 54 (73.5%) 321 (68.7%)
Female 27 (32.9%) 46 (28.0%) 19 (26.5%) 146 (31.3%)
Age (years)
 Mean (SD) 57.3 (10.9) 57.2 (8.0) 0.964 52.9 (11.8) 53.5 (10.5) 0.654
Primary location 0.994 0.334
Upper 1/3 26 (31.7%) 52 (31.7%) 26 (36.0%) 130 (27.8%)
Middle 1/3 24 (29.3%) 49 (29.9%) 19 (25.5%) 152 (32.5%)
Lower 1/3 32 (39.0%) 63 (38.4%) 28 (38.5%) 185 (39.7%)
T stage at diagnosis 0.266 0.070
 T3 5 (6.1%) 19 (11.6%) 15 (20.3%) 144 (30.8%)
 T4a 60 (73.2%) 120 (73.2%) 54 (73.3%) 275 (58.9%)
 T4b 17 (20.7%) 25 (15.2%) 5 (6.3%) 48 (10.2%)
N stage at diagnosis 0.295 0.118
 N0 1 (1.2%) 2 (1.2%) 1 (1.0%) 3 (0.7%)
 N1 19 (23.2%) 42 (25.6%) 9 (12.7%) 88 (18.9%)
 N2 34 (41.5%) 60 (36.6%) 27 (37.3%) 149 (32.0%)
 N3a 26 (31.7%) 44 (26.8%) 32 (44.0%) 161 (34.6%)
 N3b 2 (2.4%) 16 (9.8%) 4 (5.1%) 64 (13.8%)
Lymphadenectomy 0.625 0.121
 D0/D1 8 (9.8%) 21 (12.8%) 5 (7.1%) 62 (13.3%)
 D2 74 (90.2%) 143 (87.2%) 68 (92.9%) 405 (86.7%)

IPTW, inverse probability of treatment weight; CRT, chemoradiotherapy.