Table 2.
Gene lists of seven DNA damage repair (DDR) pathways.
| BER | NER | MMR | HR | NHEJ | FA | TLS |
|---|---|---|---|---|---|---|
| UNG | XPC | PMS2 | XRCC3 | XRCC6 | UBE2T | SHPRH |
| TDP1 | XPA | PMS1 | XRCC2 | XRCC5 | FANCM | REV3L |
| TDG | POLE3 | MSH6 | TOP3A | XRCC4 | FANCL | REV1 |
| POLB | POLE | MSH3 | SLX1A | PRKDC | FANCI | POLQ |
| PARP1 | ERCC6 | MSH2 | SHFM1 | POLM | FANCD2 | POLN |
| FEN1 | ERCC5 | MLH3 | RBBP8 | POLL | FANCC | POLK |
| APEX2 | ERCC4 | MLH1 | RAD52 | NHEJ1 | FANCB | POLH |
| APEX1 | ERCC2 | EXO1 | RAD51 | LIG4 | FANCA | POLI |
| LIG1 | ERCC1 | RAD50 | TP53BP1 | FANCE | ||
| LIG3 | CUL5 | PALB2 | FANCF | |||
| NBS1 | FANCG | |||||
| MUS81 | ||||||
| MRE11 | ||||||
| GEN1 | ||||||
| EME1 | ||||||
| BRIP1 | ||||||
| BRCA2 | ||||||
| BRCA1 | ||||||
| BLM | ||||||
| BARD1 | ||||||
| RAD51B | ||||||
| RAD54B | ||||||
| WRN |