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Model simulation comparison of IL-6 between the proposed model Equation (15) (solid line) and its alternate versions, AV-1, Equation (A4) (dashed line) and, AV-2, Equation (A5) (dotted line), against experimental data (circle) (mean ± SD) in response to endotoxin challenge of 3 mg/kg (top) and 12 mg/kg (bottom).
