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. Author manuscript; available in PMC: 2020 Oct 30.
Published in final edited form as: Leukemia. 2020 Jun 9;34(9):2295–2304. doi: 10.1038/s41375-020-0906-x

Figure 1. The schematic presentation of chicken β-globin locus, in which the first vertebrate chromatin insulator, cHS4, was identified.

Figure 1.

The cHS4 located at the 5’ boundary of chicken β-globin genes possesses both enhancer blocking and chromatin barrier activities in endogenous and ectopic chromatin sites.