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Molecular classification of MYC-driven aggressive mature B-cell lymphoma based on IHC, FISH and NGS
The block color represents the type of rearrangement and mutational status lined by expression of MYC and Ki-67. Categories I and II are included in the aggressive type (K2 group) and Category III (K1 group) is a less aggressive type than the others. IHC: immunohistochemistry, FISH: fluorescence in situ hybridization, NGS: next generation sequencing, DLBCL: diffuse large B-cell lymphoma.
