Table 1. Summary of antimicrobial point-of-care test strategies.
| Strategy | Antibiotic(s) for which resistance is tested |
Intended treatment regimen based on test result | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| A | + | B | No resistance to A | Resistance to A | Resistance to A + B | |||||
| Strategy A | Ciprofloxacin | NA | NA | Ciprofloxacin | + | Ceftriaxone | Azithromycin | + | Ceftriaxone | NA |
| Strategy B | Azithromycin | + | Ciprofloxacin | Azithromycin | + | Ceftriaxone | Ciprofloxacin | + | Ceftriaxone | Ceftriaxone |
| Strategy C | Ciprofloxacin | + | Azithromycin | Ciprofloxacin | + | Ceftriaxone | Azithromycin | + | Ceftriaxone | Ceftriaxone |
| Strategy D | Azithromycin | NA | NA | Azithromycina,b | NA | NA | Ciprofloxacin | + | Ceftriaxone | NA |
| Strategy E | Ciprofloxacin | NA | NA | Ciprofloxacinb | NA | NA | Azithromycin | + | Ceftriaxone | NA |
| Standard care | No resistance testing is done. Standard care is ceftriaxone 500 mg and azithromycin 1 g dual therapy [6]. | |||||||||
NA: not applicable.
a Dose given: 2 g.
b If incorrect test result and treatment fails, ceftriaxone is given.
Bold font indicates standard care antibiotics, i.e. azithromycin and ceftriaxone dual therapy.
Unless otherwise stated, doses are: ceftriaxone 500 mg; azithromycin 1 g; ciprofloxacin 500 mg.