Table 2.
Summary of operative treatment of outcomes of hepatic epithelioid hemangioendothelioma with survival data in reviewed literatures
| Author (year) | No. | Diagnostic methods | Tumor size, mean, cm | Metastasis | Operative approach | Recurrence rate, % | Survival, % |
|---|---|---|---|---|---|---|---|
| Konstantinidis et al. (2018) [1] | 67 | 14.8 | NA | LR or LT | NA | 83.4 (5-year) | |
| Lai et al. (2017) [2] | 149 | Percutaneous and/or surgical biopsy | NA | Lung, breast | LT and adjuvant therapy | 24.8% | 81 (5-year) |
| Dong et al. (2015) [3] | 3 | Liver biopsy | NA | NA | LR and RFA, or LT | 0 | 100 (3-year) |
| Remiszewski et al. (2014) [4] | 10 | Liver biopsy during diagnostic laparoscopy | 5.1 | Lymph node metastases | LT | 0 | 90 (5-year) |
| Noh et al. (2020) [5] | 19 | Liver biopsy | 3.53 | NA | LR, LR + chemotherapy, LT + radiation therapy, LT + chemotherapy | NA | 88 (5-year) |
| Wang et al. (2018) [6] | 1 | Liver biopsy | 4.7 | No | LR + chemotherapy | 0 | 100 (15-year) |
| Sanduzzi-Zamparelli et al. (2020) [7] | 11 | Surgical specimens, needle biopsy or “wedge-biopsy” | Lung, Lymph node metastases | LR or LT | 36.4 | 100 (5-year) | |
| Orlando et al. (2013) [8] | 108 | Percutaneous needle, surgical, or combined biopsies | NA | Osseous and peritoneal localizations | LT | NA | 72 (5-year) |
| Jung et al. (2016) [9] | 6 | Liver biopsy | NA | NA | HR or LT | 16.7 | 83.3 (5-year) |
| Abdoh et al. (2016) [10] | 1 | Liver biopsy | NA | Intrahepatic metastasis | LT | 100 | 0 (1-year) |
| Theodosopoulos et al. (2013) [11] | 5 | Liver biopsy | 4 | Intrahepatic metastasis | Surgical resection with a non-formal hepatectomy or wedge resection. | 40 | 60 (2-year) |
| Grotz et al. (2010) [12] | 22 | Liver biopsy | NA | Lung, peritoneum, bone, brain and skin | LR or LT | 40 | 62 (LR, 5-year), 46 (LT, 5-year) |
| Wang et al. (2012) [13] | 21 | Surgical specimens | NA | Lung metastases, diaphragm/abdominal-wall metastases | LR, LR followed by TACE,or LT | NA | 74.1 (LR, 3-year), 33.3 (LR followed by TACE, 3-year), 0 (LT, 3-year), |
| Thomas et al. (2012) [14] | 7 | Liver biopsy, diagnostic laparoscopy, surgical specimens | 3.6 | Lung | Hepatectomy or LT | 43 | 83 (5-year) |
| Krasnodębski et al. (2020) [15] | 18 | Liver biopsy | NA | Hilar lymph nodes | LT | 0 | 41.3 (5-year) |
| Thin et al. (2010) [16] | 1 | Liver biopsy | NA | Intrahepatic metastasis | LT | 0 | 100 (5-year) |
| Lin et al. (2015) [17] | 1 | Surgical specimens | NA | No | LT | 0 | 100 (5-year) |
| Samuk et al. (2016) [18] | 1 | Liver biopsy | NA | Lung | LT | 0 | 100 (5-year) |
| Sundar et al. (2015) [19] | 11 | Liver biopsy | NA | NA | LT | NA | 78.7 (5-year) |
| Groeschl et al. (2014) [20] | 12 | Liver biopsy, surgical specimens | NA | NA | Segmental resection, lobectomy/extended resection, LT | NA | 57 (LR, 1-year), 80 (LT, 1-year), |
LR liver resection, LT liver transplantation, RFA radiofrequency ablation, HR hepatic resection, TACE transcatheter arterial chemoembolization, NA not available