Table 1.

Different physicochemical parameters for ACE2 analyzed by ProtParam and Protscale tools.

Lowest		Highest			Lowest		Highest			Lowest		Highest
Buried residues %					Polarity/Zimmerman					Average flexibility
Position	Score	Position	Score		Position	Score	Position	Score		Position	Score	Position	Score
479	1.322	755	11.222		755	0.101	769	39.468		372	0.381	217	0.497
478	1.333	756	11.211		756	0.116	770	39.453		460	0.388	790	0.491
477	1.522	751	10.956		757	0.116	771	39.453		387	0.387	768	0.493
474	1.611	752	10.956		758	0.14	772	34.117		458	0.387	736	0.492
476	1.644	11	10.744		7	1.033	479	33.992		240	0.386	767	0.492
Hphob./Hopp and Woods					Relative mutability					Bulkiness
Position	Score	Position	Score		Position	Score	Position	Score		Position	Score	Position	Score
745	−1.756	770	2.300		264	51.111	60	111.222		399	11.472	742	19.523
746	−1.700	771	2.300		462	52.333	61	111.000		217	11.602	756	19.476
758	−1.578	769	2.156		591	52.889	55	107.778		398	11.619	757	19.457
742	−1.556	772	2.000		271	53.333	57	107.333		397	11.698	745	19.309
743	−1.556	768	1.822		592	54.556	443	107.333		549	11.796	758	19.279
Accessible residues (%)
Position			Score							Position			Score
746			3.622							773			8.344
377			3.778							772			8.1
745			3.822							110			7.944
459			3.844							770			7.911
558			3.911							771			7.911