Table 3.
<35 years of age | ≥ 35 years of age | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Group A | Group B | Group C | Group D | Group E | P | Group A | Group B | Group C | Group D | Group E | P | |
Cycles (n) | 1425 | 844 | 206 | 183 | 120 | 144 | 269 | 107 | 39 | 25 | ||
Preterm birth (<37weeks) |
11.77a,b,c (91/773) |
39.45 (215/545) |
33.33 (44/132) |
42.70 (38/89) |
4.55d (2/44) |
0.000 |
8.20a,b (5/61) |
35.0 (56/160) |
25.0 (13/52) |
16.67 (2/12) |
16.67 (1/6) |
0.001 |
Singleton |
8.67a (67/773) |
3.30 (18/545) |
6.82 (9/132) |
3.37 (3/89) |
4.55 (2/44) |
0.001 |
4.92 (3/61) |
5.62 (9/160) |
7.69 (4/52) |
0.0 (0/12) |
0.0 (0/6) |
0.755 |
Twin |
3.10a,b,c (24/773) |
36.15 (197/545) |
26.51 (35/132) |
39.33 (35/89) |
0.0d (0/44) |
0.000 |
3.28a,b (2/61) |
29.38 (47/160) |
17.31 (9/52) |
16.67 (2/12) |
16.67 (1/6) |
0.000 |
Gestational age (weeks) | 38.70 ± 1.94a,b,c | 37.37 ± 2.52 | 37.59 ± 2.52 | 36.86 ± 3.33 | 39.18 ± 1.91d | 0.000 | 38.72 ± 1.23a,b,c | 37.61 ± 2.33 | 37.66 ± 2.89 | 37.00 ± 3.43 | 38.32 ± 0.86d | 0.022 |
Singleton | 38.80 ± 1.83 | 38.94 ± 1.71 | 38.51 ± 2.18 | 39.00 ± 1.58 | 39.18 ± 1.91 | 0.325 | 38.81 ± 1.56 | 38.59 ± 2.14 | 38.76 ± 1.97 | 38.52 ± 1.71 | 38.32 ± 0.86 | 0.951 |
Twin | 35.32 ± 1.47 | 36.04 ± 2.32 | 36.02 ± 2.37 | 35.15 ± 3.01 | / | 0.095# | 36.20 ± 0.40 | 35.98 ± 1.63 | 35.06 ± 3.21 | 34.29 ± 4.99 | / | 0.330# |
Birth height (mm) | 49.51 ± 2.3a,b,c | 47.72 ± 3.21 | 48.23 ± 2.41 | 46.61 ± 4.26 | 49.89 ± 2.22d | 0.000 | 49.77 ± 1.85a,b,c | 48.03 ± 2.70 | 47.95 ± 3.75 | 48.31 ± 5.70 | 49.75 ± 0.96d | 0.000 |
Singleton | 49.68 ± 2.27 | 49.82 ± 1.98 | 49.88 ± 1.73 | 49.53 ± 1.44 | 49.88 ± 2.22 | 0.838 | 49.93 ± 1.76 | 49.50 ± 2.39 | 49.77 ± 2.41 | 50.00 ± 2.00 | 49.75 ± 0.96 | 0.868 |
Twin | 46.66 ± 2.40 | 46.72 ± 2.95 | 46.97 ± 2.20 | 45.50 ± 4.32 | / | 0.113# | 46.75 ± 0.35 | 46.90 ± 1.91 | 45.70 ± 3.70 | 45.83 ± 6.83 | / | 0.155# |
Birth weight (kg) | 3.16 ± .054a,b,c | 2.73 ± 0.61 | 2.79 ± 0.62 | 2.57 ± 0.66 | 3.19 ± 0.43d | 0.000 | 3.12 ± 0.51a,b,c | 2.76 ± 0.60 | 2.81 ± 0.75 | 2.55 ± 0.88 | 3.30 ± 0.29d | 0.000 |
Singleton | 3.22 ± 0.50 | 3.27 ± 0.51 | 3.24 ± 0.52 | 3.17 ± 0.33 | 3.19 ± 0.43 | 0.583 | 3.36 ± 0.49 | 3.22 ± 0.50 | 3.24 ± 0.49 | 3.26 ± 0.45 | 3.30 ± 0.29 | 0.666 |
Twin | 2.34 ± 0.43 | 2.48 ± 0.45 | 2.44 ± 0.42 | 2.31 ± 0.54 | / | 0.113# | 2.55 ± 0.25 | 2.43 ± 0.34 | 2.24 ± 0.52 | 2.00 ± 0.82 | / | 0.142# |
Still birth |
0.0 (0/773) |
0.0 (0/545) |
0.0 (0/132) |
0.0 (0/89) |
0.0 (0/44) |
/ |
0.0 (0/61) |
0.0 (0/160) |
0.0 (0/52) |
0.0 (0/12) |
0.0 (0/6) |
/ |
Congenital anomalies |
1.64 (13/795) |
1.60 (13/811) |
1.09 (2/184) |
1.52 (2/132) |
2.27 (1/44) |
0.958 |
0.0 (0/63) |
0.0 (0/217) |
0.0 (0/68) |
0.0 (0/15) |
0.0 (0/6) |
/ |
Sex ratio(male/female) |
1.30 (450/345) |
1.43 (477/334) |
1.10 (97/87) |
1.46 (78/54) |
0.83 (20/24) |
0.445 |
1.43 (37/26) |
1.22 (119/98) |
1.16 (37/31) |
0.63 (6/9) |
1.00 (3/3) |
0.632 |
Low birth weight (<2500 g) in singleton |
7.04a,b,c (56/795) |
27.25 (221/811) |
28.26 (52/184) |
34.09 (45/132) |
4.55d (2/44) |
0.000 |
6.34a,b (4/63) |
29.03 (63/217) |
27.94 (19/68) |
13.33 (2/15) |
0.0 (0/6) |
0.002 |
Singleton |
4.02 (32/795) |
4.44 (36/811) |
4.35 (8/184) |
4.55 (6/132) |
4.55 (2/44) |
0.977 |
3.17 (2/63) |
2.76 (6/217) |
1.47 (1/68) |
0.0 (0/1) |
0.0 (0/6) |
0.833 |
Twin |
3.02a,b,c (24/795) |
22.81 (185/811) |
23.91 (44/184) |
29.54 (39/132) |
0.0d (0/44) |
0.000 |
3.17a,b (2/63) |
26.27 (57/217) |
26.47 (18/68) |
13.33 (2/15) |
0.0 (0/6) |
0.001 |
Very low birth weight (<1500 g) in singleton |
0.75a,c (6/795) |
2.84 (23/811) |
1.63 (3/184) |
5.30 (7/132) |
0.0 (0/44) |
0.001 |
0.0c (0/63) |
2.76 (6/217) |
2.94 (2/68) |
13.33 (2/15) |
0.0 (0/6) |
0.045 |
Singleton |
0.63 (5/795) |
0.12 (1/811) |
0.54 (1/184) |
0.0 (0/132) |
0.0 (0/44) |
0.324 |
0.0 (0/63) |
0.5 (1/217) |
0.0 (0/68) |
0.0 (0/15) |
0.0 (0/6) |
0.879 |
Twin |
0.12a,c (1/795) |
2.72 (22/811) |
1.09 (2/184) |
5.30 (7/13) |
0.0 (0/44) |
0.000 |
0.0c (0/63) |
2.30 (5/217) |
2.94 (2/68) |
13.33 (2/15) |
0.0 (0/6) |
0.029 |
#comparison among groups A–D. P < .05 was considered statistically significant
aP < .05 compared to group B
bP < .05 compared to group C
cP < .05 compared to group D
dP < .05 between groups D and E