Table 1.
Baseline demographic and cyst characteristics on initial imaging in Fukuoka-negative and Fukuoka-positive groups
| Characteristic | Fukuoka negative* (n=802) | Fukuoka positive* (n=299) | Total (N=1101) | p Value |
|---|---|---|---|---|
| Female sex | 477 (59.5) | 147 (49.2) | 624 (56.7) | 0.002 |
| Age, mean (SD), years | 65.8 (12.9) | 65.6 (14.3) | 65.7 (13.3) | 0.74 |
| Race | <0.001 | |||
| White | 737 (91.9) | 248 (83.5) | 985 (89.6) | |
| Caucasian | 28 (3.5) | 12 (4.1) | 40 (3.6) | |
| Unknown | 37 (4.6) | 37 (12.5) | 74 (6.7) | |
| Type of imaging | 0.03 | |||
| CT | 570 (71.1) | 205 (68.6) | 775 (70.4) | |
| MRI/MRCP | 79 (9.9) | 19 (6.4) | 98 (8.9) | |
| EUS | 153 (19.1) | 75 (25.1) | 228 (20.7) | |
| Indication for initial imaging study | <0.001 | |||
| Abdominal pain | 158 (19.7) | 64 (21.4) | 222 (20.2) | |
| Jaundice | 9 (1.1) | 8 (2.7) | 17 (1.5) | |
| Pancreatitis | 23 (2.9) | 32 (10.7) | 55 (5.0) | |
| Other | 592 (73.8) | 186 (62.2) | 778 (70.7) | |
| Unknown | 20 (2.5) | 9 (3.0) | 29 (2.6) | |
| Cyst diagnosis | <0.001 | |||
| Suspected branched duct—IPMN | 97 (12.1) | 49 (16.4) | 146 (13.3) | |
| Suspected main duct—IPMN | 0 (0.0) | 18 (6.0) | 18 (1.6) | |
| Suspected mixed—IPMN | 0 (0.0) | 30 (10.0) | 30 (2.7) | |
| Presumed branched duct—IPMN | 705 (87.9) | 202 (67.6) | 907 (82.4) | |
| No. of cysts | 0.04 | |||
| 1 | 558 (69.6) | 211 (70.6) | 769 (69.8) | |
| 2 | 108 (13.5) | 26 (8.7) | 134 (12.2) | |
| 3 | 35 (4.4) | 8 (2.7) | 43 (3.9) | |
| 4 | 6 (0.7) | 3 (1.0) | 9 (0.8) | |
| ≥5 | 95 (11.8) | 51 (17.1) | 146 (13.3) | |
| Location of cyst in pancreas† | <0.001 | |||
| Head | 298 (37.2) | 152 (53.0) | 450 (41.3) | |
| Neck | 88 (11.0) | 23 (8.0) | 111 (10.2) | |
| Body | 228 (28.4) | 49 (17.1) | 277 (25.4) | |
| Tail | 188 (23.4) | 63 (22.0) | 251 (23.0) | |
| Size of largest cyst (mm)† | <0.001 | |||
| Median (range) | 10 (0.0–29.0) | 28.3 (0.0–130.0) | 11 (0.0–130.0) | |
| Cyst size group† (cm) | <0.001 | |||
| <1 | 395 (49.3) | 9 (13.5) | 434 (39.8) | |
| 1 to <2 | 319 (39.8) | 55 (19.0) | 374 (34.3) | |
| 2 to <3 | 88 (11.0) | 57 (19.7) | 145 (13.3) | |
| ≥3 | 0 (0.0) | 138 (47.8) | 138 (12.6) | |
| Family history of pancreatic cancer | 0.13 | |||
| Yes | 34 (4.2) | 19 (6.4) | 53 (4.8) | |
| No | 753 (93.9) | 278 (93.0) | 1031 (93.6) | |
| Unknown | 15 (1.9) | 2 (0.7) | 17 (1.5) | |
| Follow-up, years, median (range) | 4.9 (0.5–16.5) | 2.2 (0.0–15.6) | 4.2 (0.0–16.5) | <0.001 |
*
Values are presented as number and percentage of patients unless specified otherwise.
†
Missing in the Fukuoka-positive group are location of cyst (n=12), size of largest cyst and cyst size group (n=10).
EUS, endoscopic ultrasonography; IPMN, intraductal papillary mucinous neoplasm; MRCP, MR cholangiopancreatography.