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. 2020 Sep 15;22(9):1030. doi: 10.3390/e22091030

Table A1.

Significant FASs reported by TMEA in constraints 1–3. The p-values were clustered using the k-means clustering algorithm with a cluster number of 6 (cluster ID 1–6). The corresponding heatmap is depicted in Figure 4.

cID MapMan Annotation (FAS) cID MapMan Annotation (FAS)
1 cell wall.cell wall proteins 4 major CHO metabolism
1 cell wall.cell wall proteins.AGPs 4 major CHO metabolism.degradation
1 cell wall.cell wall proteins.AGPs.AGP 4 major CHO metabolism.degradation.starch
1 cell wall.pectin*esterases.misc 4 misc.invertase/pectin methylesterase inhibitor family protein
1 lipid metabolism.FA desaturation 4 not assigned.no ontology.DC1 domain containing protein
1 lipid metabolism.FA desaturation.desaturase 4 not assigned.unknown
1 misc.beta 1,3 glucan hydrolases 4 RNA.regulation of transcription.AP2/EREBP, APETALA2/Ethylene-responsive element binding protein family
1 misc.beta 1,3 glucan hydrolases.glucan endo-1,3-beta-glucosidase 4 RNA.regulation of transcription.C2C2(Zn) CO-like, Constans-like zinc finger family
1 misc.glutathione S transferases 4 RNA.regulation of transcription.C2C2(Zn) DOF zinc finger family
1 misc.nitrilases, *nitrile lyases, berberine bridge enzymes, reticuline oxidases, troponine reductases 4 RNA.regulation of transcription.MYB-related transcription factor family
1 misc.O-methyl transferases 4 RNA.regulation of transcription.Psudo ARR transcription factor family
1 misc.protease inhibitor/seed storage/lipid transfer protein (LTP) family protein 4 secondary metabolism.isoprenoids.terpenoids
1 nucleotide metabolism.synthesis.purine 4 secondary metabolism.phenylpropanoids.lignin biosynthesis
1 protein 4 stress.abiotic
1 protein.degradation.AAA type 4 stress.abiotic.cold
1 protein.synthesis 4 stress.biotic.respiratory burst
1 protein.synthesis.ribosomal protein 4 transport.sulfate
1 protein.synthesis.ribosomal protein.eukaryotic 5 cell wall
1 protein.synthesis.ribosomal protein.eukaryotic.40S subunit 5 cell wall.modification
1 protein.synthesis.ribosomal protein.eukaryotic.60S subunit 5 misc
1 protein.synthesis.ribosomal protein.prokaryotic.chloroplast 5 secondary metabolism
1 protein.synthesis.ribosomal protein.prokaryotic.chloroplast.50S subunit 5 secondary metabolism.flavonoids
1 protein.synthesis.ribosome biogenesis 5 secondary metabolism.flavonoids.anthocyanins
1 protein.synthesis.ribosome biogenesis.Pre-rRNA processing and modifications 5 secondary metabolism.flavonoids.anthocyanins.anthocyanin 5-aromatic acyltransferase
1 protein.synthesis.ribosome biogenesis.Pre-rRNA processing and modifications.snoRNPs 5 secondary metabolism.flavonoids.dihydroflavonols
1 protein.synthesis.ribosome biogenesis.Pre-rRNA processing and modifications.WD-repeat proteins 5 stress
1 redox.glutaredoxins 5 stress.biotic
1 RNA.regulation of transcription.ARR 5 transport
1 RNA.regulation of transcription.NAC domain transcription factor family 6 cell wall.degradation
1 RNA.regulation of transcription.WRKY domain transcription factor family 6 cell wall.degradation.mannan-xylose-arabinose-fucose
1 secondary metabolism.simple phenols 6 DNA.synthesis/chromatin structure.retrotransposon/transposase
1 signaling 6 DNA.synthesis/chromatin structure.retrotransposon/transposase.gypsy-like retrotransposon
1 signaling.in sugar and nutrient physiology 6 hormone metabolism
1 signaling.receptor kinases.DUF 26 6 hormone metabolism.auxin
1 signaling.receptor kinases.misc 6 minor CHO metabolism
1 signaling.receptor kinases.wall associated kinase 6 minor CHO metabolism.trehalose
1 signaling.receptor kinases.wheat LRK10 like 6 minor CHO metabolism.trehalose.potential TPS/TPP
1 stress.biotic.PR-proteins.plant defensins 6 misc.gluco-, galacto- and mannosidases
1 transport.Major Intrinsic Proteins 6 not assigned.no ontology.glycine rich proteins
2 amino acid metabolism.synthesis 6 not assigned.no ontology.pentatricopeptide (PPR) repeat-containing protein
2 amino acid metabolism.synthesis.aspartate family 6 PS.lightreaction
2 development.storage proteins 6 PS.lightreaction.photosystem II
2 hormone metabolism.auxin.induced-regulated-responsive-activated 6 PS.lightreaction.photosystem II.LHC-II
2 nucleotide metabolism.synthesis 6 secondary metabolism.flavonoids.chalcones
2 protein.synthesis.ribosomal protein.eukaryotic.60S subunit.L7A 6 secondary metabolism.flavonoids.flavonols
2 protein.synthesis.ribosomal protein.prokaryotic 6 secondary metabolism.phenylpropanoids
2 signaling.calcium 6 signaling.light
2 stress.biotic.receptors 6 transport.ABC transporters and multidrug resistance systems
2 transport.Major Intrinsic Proteins.PIP 6 transport.sugars
3 misc.cytochrome P450
3 misc.GDSL-motif lipase
3 misc.peroxidases
3 signaling.receptor kinases
3 stress.biotic.PR-proteins