Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 19:1–17. doi: 10.1080/07391102.2020.1832577

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Informa UK Limited, trading as Taylor & Francis Group

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

PMC Copyright notice

Figure 2. — 3D structural views of ligand-binding site. The 3D structures display H-bond interactions (green dashed lines) of ligands (a) amarogentin (b) kutkin, (c) ἀ-amyrin, (d) belladonnine, (e) eufoliatorin, (f) glycyrrhetic acid, (g) piperine and (h) represent the color intensity of hydrogen bonds with the Angiotensin-converting enzyme-2 (1R42). The i, j, k, l, m, n, o demonstrated the 2D structural views of ligand-binding site of amarogentin, kutkin, ἀ-amyrin, belladonnine, eufoliatorin, glycyrrhetic acid, piperine and p represents the H-bonding (dark green circles associated with the green dashed lines); van der Waals forces (medium light green circles); carbon-oxygen dipole-dipole interaction (light green circles with dashed lines); alkyl-pi interactions (light pink circles with dashed lines); T-shaped pi-pi stacking and (parallel) pi-pi stacking (both indicated with dark violet circles); cation-pi interaction (orange circle). The blue halo surrounding the interacting residues represents the solvent accessible surface that is proportional to its diameter. Images were generated using Discovery Studio Visualizer 4.5.