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. 2020 Oct 17;24(9):920–927. doi: 10.1007/s12603-020-1498-x

Table 3.

Diagnostic and Management Program for an Older Individual who has Deficits on the FRAIL Questionnaire (Copyright Saint Louis University and John E. Morley)

Potential Deficits
Fatigue: Exclude Depression
Exclude Sleep Apnea
Measure TSH, Vitamin B12 and Hemoglobin
Exclude low blood pressure or orthostasis resistance or Aerobic: Aerobic and Resistance exercise
Leucine enriched essential amino acid supplement
Measure bioavailable vitamin D and replace if low
Illnesses: Remove inappropriate medications including those causing side effects
Reduce Polypharmacy
Loss of Weight: Exclude depression
Stop drugs causing weight loss
Check for elderly abuse
Is the person paranoic (late life paranoia) or afraid being overweight will kill them?
Does the person have dysphagia?
Are there oral problems making chewing difficult?
Does the person have a nosocomial infection, e.g., Helicobacter pylori or tuberculosis?
Does the person have dementia?
Does the person have hyperthyroidism, Addison’s disease or pheochromocytoma?
Does the person have celiac disease or pancreatic insufficiency?
Does the person have eating difficulties?
Is person on low salt, low cholesterol or other therapeutic diet?
Does the person have cholecystitis?