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. 2020 Oct 23;11:580250. doi: 10.3389/fimmu.2020.580250

Figure 3.

Figure 3

Polyfunctional Index (PI) of SARS-CoV-2–specific CD4 and CD8 T-cells. The PI of antigen-specific CD4 and CD8 T-cells from 5 patients was calculated as previously described (18, 20) for each antigen stimulation. Data are expressed after subtraction of “background polyfunctionality” of medium-stimulated cells (Δ PI). Dotted lines correspond to PI positivity threshold as determined at 3SD of 30 negative controls measures for CD4 and CD8 T-cells. Bars are shown as mean ± SEM. LT CD4: CD4 T-cells, LT CD8: CD8 T-cells.