Table 1.
Clinical characteristics, comorbidities, severity scores, nonspecific markers, metabolic parameters at the time of enrollment.
| Variable | Value | Normal range |
|---|---|---|
| Number of patients | 15 | |
| Patients’ characteristics | ||
| Age (y.o.) | 66 [60; 72]/(54|75) | |
| Gender (male) | 12 (80) | |
| BMI (kg/m²) | 29 [24.5; 32]/(22|43) | |
| Comorbidities | ||
| Diabetes | 4 (26.7) | |
| Hypertension | 7 (46.7) | |
| Obesity | 6 (40) | |
| BMI | 1 (6.7) | |
| COPD | 2 (13.3) | |
| Asthma | 1 (6.7) | |
| SAS | 2 (13.3) | |
| Smoker | 2 (13.3) | |
| Cancer | 5 (33.3) | |
| On admission | ||
| Delay 1st Symptoms | 9 [7; 14]/(1|18) | |
| SAPS2 | 49 [42; 65]/(22|80) | |
| SOFA | 7 [4; 8]/(4|12) | |
| SOFA resp | 3 [3; 4]/(0|4) | |
| Corticosteroids | 3 (20) | |
| Nonspecific markers of inflammation | ||
| PCT (miss=2) | 0.9 [0.5; 3.1]/(0.1|37) | |
| CRP (miss=1) mg/ml | 174.4 [134; 284]/(85|389.2) | 0;0–10.0 |
| LDH | 439.5 [397; 525]/(388|885) | 120–246 |
| Ferritin (miss=3) (µg/l) | 888.5 [451; 2385]/(348|7200) | 22–322 |
| Ddimers (miss=1) (µg/l) | 1742 [1599; 3220]/(804|10000) | 45–500 |
| Fibrinogen (miss=2) (g/l) | 7.8 [6.5; 8.2]/(4.3|9.9) | 1.7–4 |
| C3 (miss=7) (g/l) | 1.6 [1.4; 1.8]/(1.2|2.4) | 0.9–1.7 |
| C4 (miss=7) (g/l) | 0.4 [0.3; 0.4]/(0.3|0.5) | 0.12–0.36 |
| Metabolic parameters | ||
| Albuminemia (miss=1) (g/l) | 25.5 [23.1; 27.4]/(18.2|31.5) | 35–52 |
| Cholesterol (miss=8) (g/l) | 3.2 [2.5; 4]/(1.8|4) | < 2 |
| TG (miss=4) (g/l) | 2.1 [1.3; 2.4]/(1.1|2.8) | <1.5 |
| Glycemia (g/l) | 1.5 [1.2; 1.8]/(0.9|3.3) | <1.2 |
| Lactate (mM/l) | 1.3 [1; 1.5]/(0.8|1.6) | <2 |
| Outcomes | ||
| VAP | 4 (26.7) | |
| Delay before VAP (miss=11) | 13.5 [7; 15.5]/(1|17) | |
| ICU LOS | 12 [10; 23]/(5|30) | |
| Death | 3 (20) |
Data are expressed as medians [Interquartile IQ] or percentages (%). SAPS2: simplified acute physiological score; SOFA, sequential organ failure assessment; VAP, ventilatory acquired pneumonia; COPD, chronic obstructive pulmonary disease; SAS, sleep apnea syndrome; PCT, procalcitonin; LDH, Lactate dehydrogenase; CRP, C-reactive protein; C3, C4, complement fractions; TG, triglycerides.