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. 2020 Oct 14;11:564288. doi: 10.3389/fimmu.2020.564288

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Copyright © 2020 Jang, Lee, Jeon, Kim, Lee, Kwon, Kim, Kim, Ko and Huh

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of intrarenal cytokines and chemokines in the postischemic kidneys on day 3 after IRI. JPI-289 treatment significantly decreased the expression of IFN-γ, CCL2, and IL-2 and increased the intrarenal expression of VEGF. *P < 0.05, compared with the IRI control group (n = 6–10 in each IRI group, n = 3 in the sham control group). Kidney protein extracts were obtained from three independent experiments. Statistical analysis was performed with the Kruskal-Wallis test followed by Dunn’s test.