. 2020 Sep 15;11(3):219–227. doi: 10.30466/vrf.2019.97574.2325

Table 3.

Effect of two different doses of oregano essential oil (OEO; 150 and 300 mg kg^-1) on serum lipid profile, protein levels, uric acid, creatinine, reduced glutathione (GSH), leukocytes counts and H/L ratio

Parameters	Days	Control	OEO 150 mg kg ^-1	OEO 300 mg kg ^-1
High density lipoproteins (mg dL ^-1 )	14-21	95.00 ± 1.50	100.50 ± 1.60	105.00 ± 5.40
High density lipoproteins (mg dL ^-1 )	21-42	96.00 ± 0.63	98.50 ± 0.64	97.25 ± 0.85
L ow density lipoproteins (mg dL ^-1 )	14-21	43.71 ± 14.11	23.57 ± 12.66	26.94 ± 12.41
L ow density lipoproteins (mg dL ^-1 )	21-42	38.32 ± 6.50	28.88 ± 6.60	41.71 ± 25.78
T otal cholesterol (mg dL ^-1 )	14-21	163.10 ± 17.42	132.60 ± 19.64	149.10 ± 11.41
T otal cholesterol (mg dL ^-1 )	21-42	182.50 ± 11.52	157.40 ± 10.71	174.40 ± 21.29
T riglycerides (mg dL ^-1 )	14-21	137.90 ± 6.86	132.00 ± 15.27	109.80 ± 6.98
T riglycerides (mg dL ^-1 )	21-42	240.6 ± 45.20	150.10 ± 26.23	167.30 ± 26.65
Total protein (g dL ^-1 )	14-21	2.75 ± 0.25^b	3.50 ± 0.29^b	4.50 ± 0.65^a
Total protein (g dL ^-1 )	21-42	3.80 ± 0.58	4.00 ± 0.71	4.75 ± 0.75
Albumin (mg dL ^-1 )	14-21	0.70 ± 0.03^b	0.97 ± 0.02^a	0.98 ± 0.03^a
Albumin (mg dL ^-1 )	21-42	1.34 ± 0.25	1.27 ± 0.08	1.53 ± 0.18
Globulin (mg dL ^-1 )	14-21	2.05 ± 0.28^b	2.53 ± 0.28^b	3.77 ± 0.60^a
Globulin (mg dL ^-1 )	21-42	2.46 ± 0.63	2.73 ± 0.78	3.23 ± 0.59
Aspartate Aminotransferase (U L^-1)	14-21	173.30 ± 11.42	159.90 ± 11.68	194.50 ± 3.23
Aspartate Aminotransferase (U L^-1)	21-42	188.30 ± 1.73^b	172.7 ± 6.85^b	201.70 ± 7.90^a
A lanine aminotransferase (U L ^-1 )	14-21	15.23 ± 0.99	12.90 ± 1.60	14.77 ± 0.57
A lanine aminotransferase (U L ^-1 )	21-42	17.43 ± 0.95^b	16.73 ± 1.39^b	25.00 ± 0.57^a
Uric acid (mg dL ^-1 )	14-21	1.75 ± 0.85	2.50 ± 0.51	2.52 ± 0.50
Uric acid (mg dL ^-1 )	21-42	3.00 ± 0.58^b	4.50 ± 1.26^ab	12.00 ± 3.89^a
Creatinine (mg dL ^-1 )	14-21	0.80 ± 0.27^b	2.50 ± 0.65^ab	3.00 ± 0.91^a
Creatinine (mg dL ^-1 )	21-42	2.00 ± 0.71^b	3.75 ± 1.11^ab	6.50 ± 1.55^a
glutathione (mg mL ^-1 )	14-21	12.83 ± 0.72^b	13.78 ± 1.26^b	20.38 ± 0.81^a
glutathione (mg mL ^-1 )	21-42	13.50 ± 0.56^b	18.67 ± 0.61^a	7.63 ± 0.59^c
Total leukocyte count (×10 ³ µL ^-1 )	14-21	14.00 ± 0.60	16.60 ± 1.80	16.60 ± 0.80
Total leukocyte count (×10 ³ µL ^-1 )	21-42	28.60 ± 2.80	27.30 ± 1.40	33.30 ± 1.70
Heterophils (%)	14-21	33.30 ± 1.70	30.00 ± 0.60	28.60 ± 2.80
Heterophils (%)	21-42	30.60 ± 1.20^b	34.30 ± 0.80^ab	38.00 ± 1.50^a
Lymphocytes (%)	14-21	58.00 ± 1.50	56.30 ± 1.70	54.60 ± 1.40
Lymphocytes (%)	21-42	56.30 ± 1.80^b	62.30 ± 0.80^a	61.00 ± 1.20^a
Eosinophils (%)	14-21	5.80 ± 0.90	4.60 ± 0.30	4.80 ± 0.40
Eosinophils (%)	21-42	5.30 ± 0.30	5.00 ± 0.60	4.30 ± 0.30
Monocytes (%)	14-21	5.00 ± 0.50	4.00 ± 0.60	4.60 ± 0.30
Monocytes (%)	21-42	4.60 ± 0.60	4.00 ± 0.50	4.00 ± 0.60
Basophils (%)	14-21	0.33 ± 0.30	0.66 ± 0.30	0.66 ± 0.30
Basophils (%)	21-42	0.33 ± 0.03	0.66 ± 0.33	1.00 ± 0.00
H/L ratio	14-21	0.57 ± 0.13	0.53 ± 0.35	0.52 ± 0.20
H/L ratio	21-42	0.54 ± 0.06^b	0.55 ± 0.10^b	0.62 ± 0.12^a

^abc Different letters in each column represent a significant difference at p < 0.05.