Table 2.
Parameters | 550 – 599 g | 600 – 649 g | 650 – 699 g | >700 g | P-value | |
---|---|---|---|---|---|---|
Oxydative stress | GSH/GT ratio | 0.18 ± 0.01a | 0.19 ± 0.03a | 0.13 ± 0.02b | 0.13 ± 0.03b | ∗∗∗ |
TBARS (mmol MDA/g of fresh tissue) | 4.12 ± 1.11 | 3.66 ± 0.83 | 4.1 ± 1.22 | 3.8 ± 0.8 | NS | |
Hypoxia | HIF1α (pg/g of fresh tissue) | 148 ± 25a | 115 ± 26b | 89 ± 38c | 88 ± 34 c | ∗∗∗ |
HIF2α (pg/g of fresh tissue) | 46 ± 17.6a,b | 35.8 ± 11.3b | 64.7 ± 22.7a | 53.7 ± 21.8a,b | ∗∗ | |
Necroptosis | RIPK3 (pg/g of fresh tissue) | 2,676 ± 793 | 2,303 ± 820 | 2,217 ± 1,179 | 2,337 ± 1,346 | NS |
PGAM5 (pg/g of fresh tissue) | 2,980 ± 760 | 2,457 ± 835 | 2,557 ± 995 | 2,984 ± 1,846 | NS | |
Ferroptosis | GPX4 (U/g of fresh tissue) | 107 ± 30 | 86 ± 20 | 79 ± 50 | 71 ± 38 | NS |
Apoptosis | CASP3+7 (ratio/g of fresh tissue) | 1,368 ± 627a | 1,327 ± 433a | 1,838 ± 2,222a | 3,756 ± 3,628b | ∗ |
CASP8 (ratio/g of fresh tissue) | 23,918 ± 6,579 | 23,630 ± 5,314 | 26,197 ± 16,156 | 39,232 ± 27,616 | NS | |
CASP9 (ratio/g of fresh tissue) | 29,283 ± 6,376 | 28,761 ± 4,833 | 30,706 ± 14,616 | 41,455 ± 24,376 | NS | |
CathL (ratio/g of fresh tissue) | 80.7 ± 18.6 | 77.3 ± 12 | 74.5 ± 15.7 | 71.1 ± 19.8 | NS | |
CathD (ratio/g of fresh tissue) | 56.5 ± 5.9 | 53.7 ± 3.3 | 50.5 ± 7.4 | 51.2 ± 5.8 | NS | |
CathB (ratio/g of fresh tissue) | 73 ± 6a | 70.6 ± 5.7a | 62.3 ± 9.4b | 63 ± 7.3b | ∗∗∗ |
Values are means ± SD. Within a line, values with different superscripts differ significantly (∗P ≤ 0.05, ∗∗P ≤ 0.01, ∗∗∗P ≤ 0.001).
Abbreviation: NS, not significant.