Table 4.
Effect of dietary inclusion of selected concentrations of DCA on mortality and lesions related to histomoniasis.1,2
| Treatment | Mortality | Liver lesions | Cecal lesions |
|---|---|---|---|
| Positive-challenged control | 6/20 | 15/20 | 16/20 |
| 0.25% DCA | 10/20 | 19/20 | 19/20 |
| 0.5% DCA | 10/20 | 20/20†,∗ | 20/20∗ |
| 1% DCA | 3/20 | 14/20 | 14/20 |
Abbreviation: DCA, deoxycholic acid.
1
Post-challenge cumulative mortality and classical lesions associated with histomoniasis from day 9 post-challenge until day 13 experiment termination. Lesions were determined based on the presence or absence of classic histomoniasis characterized by target-like liver lesions and cecal cores. No lesions or mortalities as a result of histomoniasis occurred within the non-challenged control group (0/59).
2
Statistical evaluation used the chi-square test (indicated by “∗”) and Fisher's exact test (indicated by “†”) as compared to the positive-challenged control with significance at P ≤ 0.05.