Table 4.
GO cluster analysis (GEN vs. LPS).
| Levels | GO_Name | GO_ID | P value_adjusted | Gene_Count | Pop_Hit |
|---|---|---|---|---|---|
| 4, 5, 6 | Regulation of leukocyte activation | GO:0002694 | 6.62E-06 | 90 | 281 |
| 6 | Cellular response to growth factor stimulus | GO:0071363 | 6.96E-06 | 135 | 468 |
| 5, 6 | Homotypic cell-cell adhesion | GO:0034109 | 3.10E-05 | 98 | 324 |
| 5, 6 | Morphogenesis of an epithelium | GO:0002009 | 9.68E-05 | 115 | 405 |
| 5, 6 | Leukocyte cell-cell adhesion | GO:0007159 | 1.64E-04 | 87 | 291 |
| 5, 6 | Regulation of programmed cell death | GO:0043067 | 2.07E-04 | 256 | 1052 |
| 6 | Leukocyte differentiation | GO:0002521 | 3.55E-04 | 98 | 344 |
| 6 | T-cell differentiation | GO:0030217 | 7.83E-04 | 53 | 163 |
| 5, 6 | MAPK cascade | GO:0000165 | 8.21E-04 | 151 | 587 |
| 4, 5, 6 | Positive regulation of lipid metabolic process | GO:0045834 | 9.04E-04 | 31 | 80 |
| 5, 6 | I-κB kinase/NF-κB signaling | GO:0007249 | 3.22E-03 | 62 | 210 |
| 6 | Alpha-beta T-cell activation | GO:0046631 | 4.20E-03 | 31 | 87 |
| 5, 6 | Epithelial cell development | GO:0002064 | 5.28E-03 | 57 | 193 |
| 4, 5, 6 | Positive regulation of cell junction assembly | GO:1901890 | 7.16E-03 | 13 | 26 |
| 5, 6 | Regulation of Wnt signaling pathway | GO:0030111 | 7.43E-03 | 65 | 230 |
| 6 | Response to interleukin-1 | GO:0070555 | 1.08E-02 | 22 | 58 |
| 5, 6 | Positive regulation of adherens junction organization | GO:1903393 | 1.11E-02 | 12 | 24 |
Abbreviations: GEN, lipopolysaccharide-challenged group fed diet supplemented with 40 mg/kg genistein; LPS, lipopolysaccharide-challenged group; GO, gene ontology.