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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Clin Cancer Res. 2020 Jul 10;26(17):4651–4660. doi: 10.1158/1078-0432.CCR-19-4112

Figure 2. Copy number alterations associated with race and Gleason score across 4 prostate cancer cohorts.

Figure 2.

(A) Gene deletion frequencies associated with race were identified with a logistic regression model containing race, Gleason score and age (AFR: 171, EUR: 626). Solid purple points represent genes significantly associated with race (FDR < 0.05). (B) The frequency of PTEN deletions was significantly lower in AFR men (FDR < 0.05). Differences between groups were most pronounced in Gleason 6 and 7 tumors. (C) The frequency of ZFHX3 deletions was significantly higher in AFR men (FDR < 0.05).