Table 3.
Baseline demographics and wellbeing measures in APOE4 carriers vs. non-carriers.
| APOE4 Non-Carrier (n = 48) |
APOE4 Carrier (n = 17) |
p-Value | |
|---|---|---|---|
| Sex (female %) | 52 | 53 | |
| Age (years) | 66.3 ± 1.2 | 64.0 ± 1.8 | 0.298 |
| BMI (kg/m2) | 31.5 ± 0.6 | 29.3 ± 0.7 | 0.052 |
| Depressive symptoms (%) | 15.2 ± 1.8 | 15.4 ± 4.2 | 0.953 |
| EPA (%) | 1.06 ± 0.37 | 1.04 ± 0.44 | 0.807 |
| DHA (%) | 5.49 ± 1.36 | 5.73 ± 1.31 | 0.527 |
| Tension (%) | 20.9 ± 2.3 | 25.5 ± 5.3 | 0.356 |
| Depression (%) | 10.4 ± 1.8 | 9.7 ± 3.4 | 0.855 |
| Anger (%) | 8.5 ± 1.4 | 12.2 ± 3.1 | 0.214 |
| Fatigue (%) | 30.3 ± 4.1 | 23.3 ± 3.9 | 0.219 |
| Confusion (%) | 26.8 ± 2.8 | 22.3 ± 4.0 | 0.388 |
| Vigour (%) | 49.4 ± 2.7 | 52.2 ± 5.7 | 0.619 |
| TMD a (%) | −30.0 ± 4.2 | −33.6 ± 8.0 | 0.671 |
| Subjective memory complaints (%) | 41.9 ± 3.8 | 30.6 ± 6.5 | 0.137 |
| Quality of life (%) | 69.5 ± 2.0 | 72.7 ± 3.4 | 0.430 |
Values are expressed as the mean ± SEM. a Greater negative value equals better overall mood. APOE4, apolipoprotein E4; BMI, body mass index; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; TMD, total mood disturbance.