Figure 5.

Effect of HDL, DPPC, DPPC:Chol:lysoPC and DPPC:CE:lysoPC rHDLs on cholesterol efflux in vascular smooth muscle cells (VSMC) derived foam cells stimulated or not with TO90. rHDLs were added to the stimulated and non-stimulated cells in MEM-Hepes 25 mM (pH 7.4) containing 2 µg/mL ACAT inhibitor and incubated during 6 h to promote cholesterol efflux. Cholesterol efflux was calculated as described in Methods. Data represent the means ± S.D. of at least three independent measurements. Levels of significance were determined by a two-tailed Student’s t-test. * p < 0.01 compared to HDL and # p < 0.01 compared to DPPC.