REAGENT or RESOURCE	SOURCE	IDENTIFIER
Biological Samples
Human serum (Fr1 da study)	Institute of Diabetes Research, Helmholtz Center Munich	N/A
Human blood spots (Freder1k study)	Institute of Diabetes Research, Helmholtz Center Munich	N/A
Human serum (SARS-CoV-2 positive individuals, Munich Bioresource Study)	Institute of Diabetes Research, Helmholtz Center Munich	N/A
Human serum (SARS-CoV-2 positive individuals)	Institute of Virology, Technical University Munich	N/A
Chemicals, Peptides, and Recombinant Proteins
Nanoluciferase-tagged RBD	Vito Lampasona (this paper)	N/A
Nanoluciferase-tagged Nucleocapsid protein	Vito Lampasona (this paper)	N/A
Protein A-Sepharose CL-4B	GE Healthcare	GE17-0780-01
Streptavidin Sepharose High Performance	GE Healthcare	GE17-5113-01
Purified recombinant RBD	Kathrin de la Rosa (this paper)	N/A
Biotinylated purified recombinant ACE2	Kathrin de la Rosa (this paper)	N/A
Critical Commercial Assays
Nano-Glo Luciferase Assay	Promega	N1120
Experimental Models: Cell Lines
Expi293F cells	Thermo Fisher Scientific Life Technologies	A14527; RRID:CVCL_D615
Recombinant DNA
Plasmid pCMV-TnT	Promega	L5620
Plasmid IL6sp-secNluc-SARS-CoV-2-RBD	Vito Lampasona (this paper)	N/A
Plasmid Nluc-SARS-CoV-2- nucleocapsid	Vito Lampasona (this paper)	N/A
Plasmid IL6sp-secNluc-HuCoV-OC43-RBD	Vito Lampasona (this paper)	N/A
Software and Algorithms
GraphPad Prism Version 8.3.1	GraphPad Software, San Diego, CA	N/A
R v4.0.2 package finalfit v1.0.2	https://CRAN.R-project.org/doc/FAQ/R-FAQ.html	https://cran.r-project.org/web/packages/finalfit/index.html