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. 2020 Oct 29;27(2):406–409. doi: 10.1016/j.jiac.2020.10.026

Table 2.

Features of RT-qPCR, FilmArray RP v2.1, and the LUMIPULSE antigen test.

Assay Principle Strong points Weak points
RT-qPCR Detects SARS-CoV-2 RNA by PCR amplification
  • Assesses viral load quantitatively

  • High sensitivity

  • Long runtime (3–4 h)

  • Low throughput

  • Requires equipment, skilled technician

  • Results fluctuates at the late phase of infection

FilmArray RP v2.1 Detects SARS-CoV-2 RNA by PCR amplification
  • Short runtime (45 min)

  • Easy of use

  • High sensitivity

  • Qualitative assay

  • High cost

  • Requires equipment

  • Results fluctuates at the late phase of infection

LUMIPULSE antigen test Detects SARS-CoV-2 N protein by chemiluminescent enzyme immunoassay
  • Short runtime (30 min)

  • High throughput (maximum 60–120 samples /one hour)

  • Low sensitivity

  • Requires equipment

  • Results fluctuates at the intermediate phase of infection