Table 2. Adjusted HRs for vascular diseases by BMI-metabolic health status at baseline.
| MHN | MHOW | MHO | MUN | MUOW | MUO | |
|---|---|---|---|---|---|---|
| Major vascular events | ||||||
| Cases | 22,208 | 9,756 | 1,222 | 3,673 | 9,308 | 6,084 |
| Person-years | 2,263,506 | 1,058,246 | 149,650 | 163,919 | 457,010 | 317,883 |
| HR, model 1 | 1.00 (0.99–1.01) | 1.04 (1.02–1.06) | 1.08 (1.02–1.15) | 1.50 (1.45–1.55) | 1.58 (1.54–1.61) | 1.69 (1.65–1.74) |
| HR, model 2 | 1.00 (0.99–1.01) | 1.06 (1.04–1.08) | 1.08 (1.02–1.14) | 1.54 (1.49–1.60) | 1.58 (1.55–1.62) | 1.67 (1.63–1.72) |
| Major coronary events | ||||||
| Cases | 3,052 | 1,178 | 134 | 616 | 1,424 | 922 |
| Person-years | 2,320,018 | 1,087,933 | 153,411 | 173,541 | 484,710 | 336,148 |
| HR, model 1 | 1.00 (0.96–1.04) | 0.98 (0.92–1.04) | 1.02 (0.86–1.21) | 1.69 (1.56–1.83) | 1.66 (1.58–1.75) | 1.88 (1.76–2.01) |
| HR, model 2 | 1.00 (0.96–1.04) | 1.02 (0.96–1.08) | 1.05 (0.89–1.25) | 1.78 (1.65–1.93) | 1.73 (1.64–1.82) | 1.92 (1.80–2.05) |
| Ischemic heart disease | ||||||
| Cases | 15,342 | 7,527 | 1,194 | 2,353 | 6,751 | 4,825 |
| Person-years | 2,269,151 | 1,061,802 | 148,993 | 165,851 | 461,504 | 319,245 |
| HR, model 1 | 1.00 (0.98–1.02) | 1.10 (1.08–1.13) | 1.37 (1.29–1.45) | 1.39 (1.33–1.44) | 1.61 (1.57–1.65) | 1.82 (1.77–1.87) |
| HR, model 2 | 1.00 (0.98–1.02) | 1.10 (1.07–1.12) | 1.34 (1.27–1.42) | 1.41 (1.35–1.47) | 1.60 (1.56–1.64) | 1.79 (1.74–1.84) |
| Stroke | ||||||
| Cases | 17,697 | 8,352 | 1,064 | 2,905 | 7,815 | 5,118 |
| Person-years | 2,267,260 | 1,060,278 | 149,906 | 164,555 | 458,868 | 319,108 |
| HR, model 1 | 1.00 (0.98–1.02) | 1.09 (1.07–1.12) | 1.13 (1.06–1.20) | 1.50 (1.45–1.56) | 1.65 (1.61–1.69) | 1.74 (1.70–1.79) |
| HR, model 2 | 1.00 (0.98–1.02) | 1.10 (1.07–1.12) | 1.11 (1.05–1.18) | 1.54 (1.48–1.60) | 1.64 (1.61–1.68) | 1.71 (1.66–1.76) |
Multivariable models were adjusted for model 1: study region, age (5 years) and sex (men or women) and model 2: study region, age (5 years), sex (men or women), education (primary school or lower, middle school or higher), household income (<20,000 yuan/year, or ≥20,000 yuan/year), marital status (married, others), smoking status (current regular smoker, not current regular smoker), alcohol use(weekly drinker, not weekly drinker), intakes of red meat, fresh fruits and vegetables (daily, 4–6 days/week, 1–3 days/week, monthly, or never/rarely), family history of heart attack or stroke (presence or absence), and physical activity (3 groups).
BMI, body mass index; HR, hazard ratio; MHN, metabolically healthy normal weight; MHO, metabolically healthy obesity; MHOW, metabolically healthy overweight; MUN, metabolically unhealthy normal weight; MUO, metabolically unhealthy obesity; MUOW, metabolically unhealthy overweight.