Table 3. Demographic and clinical characteristics of healthy living donors and subjects with diabetic nephropathy.
| Tubulointerstitium | Glomerulus | |||||
|---|---|---|---|---|---|---|
| HLD | DN | P value (DN vs. HLD) | HLD | DN | P value (DN vs. HLD) | |
| n | 31 | 17 | 21 | 12 | ||
| Sex (females/males) | 10/12 | 5/12 | 0.4906 | 9/12 | 4/8 | 0.8663 |
| Age (years) | 47.3 ± 2.4 | 58.3 ± 2.6 | 0.0042 | 47.2 ± 2.6 | 54.8 ± 3.2 | 0.0776 |
| BMI (kg/m2) | 23.7 ± 0.1 | 27.7 ± 1.3 | 0.2544 | 23.7 ± 0.1 | 27.0 ± 1.8 | 0.3675 |
| Mean BP (mm Hg) | 93.3 ± 10.7 | 105.8 ± 3.7 | 0.2349 | 93.3 ± 10.7 | 106.9 ± 4.1 | 0.2220 |
| SCR (mg/dl) | 0.82 ± 0.06 | 2.24 ± 0.39 | 0.0002 | 0.83 ± 0.06 | 1.83 ± 0.32 | 0.0004 |
| BUN (mg/dl) | – | 68.6 ± 17.9 | – | – | 58.9 ± 11.6 | – |
| eGFR (ml/min/1.73 m2) | 104.3 ± 6.5 | 44.3 ± 6.0 | < 0.0001 | 105.4 ± 6.8 | 52.9 ± 8.8 | < 0.0001 |
BMI, body mass index; BP, blood pressure; BUN, blood urea nitrogen; DN, diabetic nephropathy; eGFR, estimated glomerular filtration rate; HLD, healthy living donor; SCR, serum creatinine. For continuous variables, values are presented as the mean ± SEM and P values were determined by Student’s t tests. For categorical variables, P values were determined by χ2 tests.