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. 2020 Sep 23;9(10):778. doi: 10.3390/pathogens9100778

Table 2.

Experimental conditions for the E. coli dose-response experiment for the selected models found in QMRAWiki [29].

Host Type Agent Strain Route # of Doses Dose Units Response Best fit Model Optimized Parameter(s) ID50
Recommended best fit model Human EIEC 1624 Oral (in milk) 3 CFU Positive stool isolation beta-Poisson α = 1.55×10−1
N50 = 2.11 × 106
2.11 × 106
High infectious dose model Human ETEC B7A Oral (in milk) 11 CFU Mild to severe diarrhea beta-Poisson α = 2.06 × 10−1
N50 = 1.28 × 108
1.28 × 108
Low infectious dose model Human ETEC B7A Oral (in milk) 7 CFU Positive stool isolation beta-Poisson α = 3.75 × 10−1
N50 = 1.78 × 105
1.78 × 105