Table 2.
Host Type | Agent Strain | Route | # of Doses | Dose Units | Response | Best fit Model | Optimized Parameter(s) | ID50 | |
---|---|---|---|---|---|---|---|---|---|
Recommended best fit model | Human | EIEC 1624 | Oral (in milk) | 3 | CFU | Positive stool isolation | beta-Poisson | α = 1.55×10−1 N50 = 2.11 × 106 |
2.11 × 106 |
High infectious dose model | Human | ETEC B7A | Oral (in milk) | 11 | CFU | Mild to severe diarrhea | beta-Poisson | α = 2.06 × 10−1 N50 = 1.28 × 108 |
1.28 × 108 |
Low infectious dose model | Human | ETEC B7A | Oral (in milk) | 7 | CFU | Positive stool isolation | beta-Poisson | α = 3.75 × 10−1 N50 = 1.78 × 105 |
1.78 × 105 |