Table 1.
Relevant markers found by the genome-wide association study (GWAS) and FST analysis and raw canonical coefficients (CC) associated to significant single nucleotide polymorphisms (SNPs). Within-class average scores for the two discriminant functions (Can1 and Can2). CC: canonical coefficients.
| SNP | GWAS | Raw CC | ||
|---|---|---|---|---|
| BTA 1 | Disease 2 | Can1 | Can2 | |
| ARS-BFGL-NGS-13673 | 1 | Ma | 0.63 | 0.52 |
| ARS-USDA-AGIL-chr2-17084934-000418 | 2 | Ma | 0.27 | 0.59 |
| ARS-USDA-AGIL-chr4-114395607-000108 | 4 | Ar, Ma | −0.19 | 0.05 |
| ARS-USDA-AGIL-chr7-12174899-000752 | 7 | Ar | −0.18 | −0.14 |
| Hapmap44668-BTA-119022 | 7 | Ar | 0.62 | −0.26 |
| ARS-USDA-AGIL-chr7-18201332-000761 | 7 | Ma | 0.66 | 0.88 |
| ARS-USDA-AGIL-chr8-84099468-000783 | 8 | Ar | −0.15 | −0.72 |
| ARS-USDA-AGIL-chr10-25594159-000176 | 10 | Ar, Ma | −0.37 | 0.15 |
| ARS-USDA-AGIL-chr11-36809347-000009 | 11 | Ar, Ma | −0.16 | 0.22 |
| ARS-BFGL-NGS-15423 | 16 | Ma | 0.02 | 0.02 |
| BovineHD1600007856 | 16 | Ma | 0.37 | 0.25 |
| BovineHD4100012725 | 16 | Ma | 0.72 | −0.11 |
| ARS-USDA-AGIL-chr17-6999864-000318 | 17 | Ma | −0.09 | −0.17 |
| ARS-USDA-AGIL-chr22-32285822-000477 | 22 | Ar, Ma | 0.19 | −0.08 |
| BovineHD2400015279 | 24 | Ar | −0.57 | 0.56 |
| ARS-USDA-AGIL-chr24-25995108-000530 | 24 | Ar, Ma | −0.17 | −0.47 |
| ARS-USDA-AGIL-chr25-1930875-000536 | 25 | Ar | −0.12 | 0.45 |
| BovineHD4100017966 | 26 | Ma | −0.02 | −0.78 |
| BovineHD2600011259 | 26 | Ma | 0.31 | 0.42 |
| BovineHD2600011282 | 26 | Ma | 0.42 | 0.5 |
| BovineHD2600014129 | 26 | Ma | 0.59 | 0.85 |
| BovineHD2800000629 | 28 | Ar | 0.56 | −1.17 |
| ARS-USDA-AGIL-chr29-39842168-000583 | 29 | Ar | −0.40 | −0.65 |
| Within-class average | ||||
| Arthrogryposis | Ar | 1.23 | −1.55 | |
| Macroglossia | Ma | 2.03 | 1.13 | |
| Healthy control | He | −1.62 | 0.16 | |
1Bos taurus chromosome; 2 Ar: arthrogryposis and Ma: macroglossia.