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. 2020 Sep 2;59(39):3709–3724. doi: 10.1021/acs.biochem.0c00458

Figure 10.

Figure 10

TCID50 infectivity results for 53 candidate compounds compared to the positive control NITD008 (blue). Candidates 14 and 43 were tested at 10 μM; all of the other candidates and the NITD008 control were tested at 25 μM. Red bars represent candidates that inhibited infectivity to <0.6 (horizontal dotted line) in the TCID50 assay and >1.0 in the cell viability assay. Yellow bars represent candidates with TCID50 activity but not flagged as active in the cell viability assay. Candidates 5* and 52* did not yield results in the TCID50 assay.