Table 1. Structure Validation for the ZIKV E/BOG Homology Model.
| 1OKE templatea (DENV E) | homology modela (ZIKV E) | |||
|---|---|---|---|---|
| atom contacts | Clashscore | 21.37 (59th percentile) | 4.46 (95th percentile) | |
| MolProbity | protein geometry | poor rotamers | 32 (9.36%) | 19 (5.94%) |
| favored rotamers | 280 (81.87%) | 273 (85.31%) | ||
| Ramachandran outliers | 6 (1.53%) | 8 (2.25%) | ||
| Ramachandran favored | 354 (90.31%) | 323 (90.99%) | ||
| MolProbity score | 3.10 (24st percentile) | 2.33 (57th percentile) | ||
| PROCHECK | Ramachandran plot | most favored | 81.8% | 84.3% |
| additional allowed | 17.6% | 14.0% | ||
| generously allowed | 0.6% | 1.2% | ||
| disallowed | 0.0% | 0.6% | ||
| residue stereochemistry | Morris classification | 1,2,3 | 1,2,2 | |
| bad contacts | 6 | 1 | ||
| overall properties | G-factors | 0.13 | –0.34 | |
| planar groups | 98.4% | 92.2% |
a
Bold entries indicate more favorable characteristics.