Wastewater management in Alaska identifies high risk areas for potential virus spillover. Geo-mapping of wastewater treatment plants was done using data from the Alaska Department of Environmental and Conservation. Types of treatment are listed for each plant (lagoon or secondary) and flow data is included. Overlap between species predicted to be susceptible and wastewater treatment plants that utilize lagoon treatment are identified as high-risk areas. High-risk sites and facilities discussed are bordered in black (Palmer; Talkeetna Lagoon), blue (City of Cold Bay; Cold Bay Lagoon), purple (Naknek; Naknek Lagoon) and red (Dillingham; Dillingham Lagoon). Marine mammal population data was obtained from a previous study (Lefebvre et al., 2016). Populations shown on the map in hexagons (represents 1–5 individuals observed at that location) and include the following species: (A) Northern fur seal (B) Stellar sea lions, (C) Northern sea otters, (D) Harbor seals, (E) Beluga whale, (F) Harbor porpoises, (G) Humpback whale. The colours of the hexagon species indicators describe predicted susceptibility; orange is high susceptibility and red is higher than human susceptibility. Grey hexagons indicate the Phoca hispida (Ringed seal), Erignathus barbatus (Bearded seal) and Phoca largha (Spotted seal) found in those areas. These species were not included in the analysis since their genomes are uncharacterized. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)