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Mean concentration–time curves of serum trastuzumab emtansine (T-DM1), serum total trastuzumab, and plasma emtansine (DM1) in patients (n = 11) with locally advanced inoperable or metastatic human epidermal growth factor receptor 2-positive breast cancer after the first dose of T-DM1 at 3.6 mg/kg every 3 weeks. Error bars are standard deviation.
