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. 2020 Oct 30;99(44):e22892. doi: 10.1097/MD.0000000000022892

Figure 4.

Figure 4

Correlation between serum levels of sTIM-3 and proinflammatory markers (A: ESR, B: MMP-3) in the sub-grouped RA patients according to the titers of ACPA. Correlation analysis of serum levels of sTIM-3 and clinical parameters (A: ESR, B: MMP-3) does not show a relationship in RA patients with high titers of ACPA (≧200U/ml). Whereas there was a significant positive correlation between clinical parameters (A: ESR, B: MMP-3) in RA patients with low titers of ACPA (<200 U/ml). ACPA = anti-citrullinated peptide antibody, MMP-3 = matrix metalloproteinase-3, RA = rheumatoid arthritis, sTIM-3 = soluble T cell immunoglobulin domain and mucin-3.