Table 2.
IC50 and CI50 values of CIS/5-FU LPHNs with different CIS to 5-FU ratios.
| Nanoparticles | CIS to 5-FU ratios (w/w) | IC50 of CIS (μM) | IC50 of 5-FU (μM) | CI |
|---|---|---|---|---|
| CIS LPHNs | – | 29.3 ± 1.5 | – | – |
| 5-FU LPHNs | – | – | 31.5 ± 1.8 | – |
| CIS/5-FU LPHNs | 5–1 | 23.9 ± 1.3 | 4.78 ± 0.5 | 0.97 |
| CIS/5-FU LPHNs | 2–1 | 18.6 ± 0.8 | 9.3 ± 0.4 | 0.93 |
| CIS/5-FU LPHNs | 1–1 | 10.3 ± 1.1 | 10.3 ± 1.2 | 0.68 |
| CIS/5-FU LPHNs | 1–2 | 8.6 ± 0.5 | 17.2 ± 1.7 | 0.84 |
| CIS/5-FU LPHNs | 1–5 | 5.06 ± 0.4 | 25.4 ± 1.3 | 0.98 |
Values represented as mean ± standard deviation (n = 10).