Table 1.
Baseline characteristics of AKI and non-AKI.
| Variable | AKI (n = 68) | Non-AKI (n = 297) | p Value |
|---|---|---|---|
| Demographic data | |||
| Age (years) | 60.1 ± 12.3 | 58.5 ± 10.5 | 0.299 |
| Male (N, %) | 31 (45.6%) | 127 (42.8%) | 0.671 |
| BMI | 24.9 ± 3.5 | 29.2 ± 3.1 | 0.334 |
| Smoke (N, %) | 17 (25.0%) | 64 (21.5%) | 0.537 |
| Drink (N, %) | 11 (16.2%) | 49 (16.5%) | 0.948 |
| Transfusion (N, %) | 6 (8.8%) | 25 (8.4%) | 0.914 |
| Comorbidities | |||
| Cerebral infarction (N, %) | 6 (8.8%) | 20 (6.7%) | 0.546 |
| Diabetes mellitus (N, %) | 8 (11.8%) | 15 (3.8%) | 0.040 |
| Coronary heart disease (N, %) | 2 (2.9%) | 20 (6.7%) | 0.238 |
| Hypertension (N, %) | 33 (48.5%) | 132 (44.4%) | 0.542 |
| Medications | |||
| ACEI (N, %) | 11 (16.2%) | 28 (9.4%) | 0.104 |
| ARB (N, %) | 11 (16.2%) | 60 (20.2%) | 0.449 |
| β-Blocker (N, %) | 31 (45.6%) | 159 (53.5%) | 0.237 |
| Statin (N, %) | 4 (5.9%) | 26 (8.8%) | 0.437 |
| CCB (N, %) | 64 (94.1%) | 285 (96.0%) | 0.503 |
| Aspirin (N, %) | 16 (23.5%) | 78 (26.3%) | 0.642 |
| Antibiotic (N, %) | 62 (91.2%) | 281 (94.6%) | 0.429 |
| NSAID (N, %) | 25 (36.8%) | 133 (44.8%) | 0.229 |
| PPI (N, %) | 65 (95.6%) | 286 (96.3%) | 0.784 |
| Laboratory data | |||
| eGFR (ml/min/1.732) | 83.8 ± 34.7 | 100.8 ± 18.2 | <0.001 |
| Scr (μmol/L) | 72.3 ± 68.1 | 70.9 ± 23.2 | 0.769 |
| Glucose (mmol/L) | 7.8 ± 2.3 | 7.0 ± 2.5 | 0.015 |
| Hb (g/L) | 130.8 ± 20.0 | 129.9 ± 19.8 | 0.739 |
| PLT (×109/L) | 212.9 ± 50.1 | 219.8 ± 63.3 | 0.400 |
| RBC (×1013/L) | 4.3 ± 0.6 | 4.3 ± 0.6 | 0.985 |
| WBC (×109/L) | 11.1 ± 3.4 | 10.0 ± 4.0 | 0.040 |
| Monocyte (×109/L) | 0.6 ± 0.4 | 0.6 ± 0.3 | 0.537 |
| Neutrophil (×109/L) | 9.3 ± 3.3 | 8.0 ± 4.0 | 0.012 |
| ALT (U/L) | 23.1 ± 21.0 | 22.9 ± 23.0 | 0.958 |
| AST (U/L) | 21.9 ± 11.1 | 21.7 ± 17.5 | 0.934 |
| GGT (U/L) | 26.9 ± 28.5 | 25.4 ± 30.7 | 0.552 |
| ADA (U/L) | 9.3 ± 2.9 | 9.5 ± 3.6 | 0.553 |
| TBIL (μmol/L) | 15.5 ± 9.0 | 16.6 ± 8.7 | 0.368 |
| LDH (U/L) | 184.0 ± 45.4 | 167.2 ± 44.7 | 0.681 |
| ALP (U/L) | 69.8 ± 24.1 | 67.7 ± 20.7 | 0.502 |
| TP (g/L) | 62.6 ± 7.7 | 64.1 ± 8.1 | 0.137 |
| A/G | 1.4 ± 0.3 | 1.4 ± 0.3 | 0.648 |
| ALB (g/L) | 35.6 ± 4.7 | 37.0 ± 5.2 | 0.039 |
| CHOL (mmol/L) | 4.6 ± 1.0 | 4.9 ± 1.2 | 0.066 |
| TG (mmol/L) | 1.2 ± 0.6 | 1.2 ± 0.8 | 0.470 |
| HDL (mmol/L) | 1.2 ± 0.3 | 1.4 ± 0.4 | 0.005 |
| LDL (mmol/L) | 2.6 ± 0.8 | 2.8 ± 0.9 | 0.054 |
| UA (μmol/L) | 208.2 ± 118.0 | 206.5 ± 101.7 | 0.915 |
| PT (s) | 10.6 ± 1.3 | 10.8 ± 1.6 | 0.261 |
| FIB (/L) | 3.3 ± 1.0 | 3.3 ± 0.9 | 0.833 |
| TT (s) | 14.5 ± 2.5 | 14.2 ± 2.3 | 0.444 |
| Intraoperative data | |||
| Posterior circulation (N, %) | 2 (2.9%) | 14 (4.7%) | 0.752 |
| Diameter of aneurysm (N, %) | 8.6 ± 7.0 | 8.4 ± 7.0 | 0.859 |
| Diameter ≥ 10 mm (N, %) | 24 (35.3%) | 95 (32.0%) | 0.600 |
| Number of aneurysm (N) | 1.1 ± 0.4 | 1.1 ± 0.3 | 0.611 |
| Multiple (N, %) | 7 (10.3%) | 27 (9.1%) | 0.758 |
| Rupture before sugery (N, %) | 56 (82.4%) | 205 (69.0%) | 0.028 |
| Blood loss in operation (ml) | 308.4 ± 249.0 | 293.7 ± 296.9 | 0.673 |
| Transfusion in operation (N, %) | 3 (4.4%) | 14 (4.7%) | 0.915 |
| Postoperative outcomes | |||
| CTA before discharge | 22 (32.4%) | 123 (41.4%) | 0.168 |
| LOS (days) | 21.6 ± 18.9 | 17.0 ± 9.5 | 0.004 |
| Death (N, %) | 7 (10.3%) | 4 (1.3%) | ＜0.001 |
BMI: body mass index; NRS2002: Nutritional Risk Screening 2002; ACEI: ACE inhibitor; ARB: angiotensin receptor blocker; CCB: calcium channel blocker; NSAID: non-steroidal anti-inflammatory drugs; PPI: proton pump inhibitors; eGFR: estimated glomerular filtration rate; Scr: serum creatinine; Hb: hemoglobin; PLT: platelet; RBC: red blood cell; WBC: white blood cell; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transpeptidase; ADA: adenosine deaminase; TBIL: total bilirubin; LDH: lactate dehydrogenase; ALP: alkaline phosphatase; TP: total protein; A/G: albumin/globulin ratio; ALB: albumin; CHOL: cholesterol; TG: triglyceride; HDL: high density lipoprotein; LDL: low density lipoprotein; UA: uric acid; PT: prothrombin time; FIB: fibrinogen; TT: thrombin time; LOS: length of stay; CTA: computed tomography angiography.