Table 5. The secretion of IL-17 and IFN-γ by CD4+ T cells activated with autologous DCs in MS patients and in healthy subjects.
Cytokine | Experimental conditions | MS patients, n = 5 | Healthy subjects, n = 5 |
---|---|---|---|
IL-17, pg/ml | Resting DCs, | 28 (8; 42) | 16 (2; 52) |
– SEB | |||
LPS-activated DCs, | 160 (115; 170) | 158 (151; 232) | |
+ SEB | |||
IFN-γ, pg/ml | Resting DCs, | 6 (5; 33) | 15 (7; 35) |
– SEB | |||
LPS-activated DCs, | 2459 (2060; 4094) | 2819 (2355; 3393) | |
+ SEB |
IFN-γ, interferon-γ; IL-17, interleukin-17; LPS, lipopolysaccharide; MS, multiple sclerosis; SEB, staphylococcal enterotoxin B.