Table 3.

Quantitative MR parameters obtained from ROIs drawn on visit 2 and propagated to visit 1. Measurements show tissue changes within the tear site only. Mean values for T2, MD and FA and eigenvalues for both visits and the difference between them are presented as mean (confidence interval); p value

Measurement	Visit 1 mean (CI)	Visit 2 mean (CI)	Difference mean (CI); p value
T2 (ms)	60.04 (49.73, 70.35)	47.34 (41.09, 53.59)	13.12 (4.82, 21.42); p = 0.01
MD (×10−3mm2s−1)	1.86 (1.72, 2.01)	1.65 (1.52, 1.77)	0.22 (0.04, 0.39); p = 0.02
FA	0.19 (0.13, 0.25)	0.26 (0.21, 0.32)	0.07 (0.01, 0.14); p = 0.03
λ1(×10−3mm2s−1)	2.23 (2.13, 2.32)	2.11 (1.94, 2.28)	0.12 (− 0.08, 0.31); p = 0.09
λ2(×10−3mm2s−1)	1.81 (1.62, 2.00)	1.63 (1.44, 1.83)	0.18 (− 0.08, 0.44); p = 0.16
λ3(×10−3mm2s−1)	1.55 (1.36, 1.74)	1.23 (1.09, 1.37)	0.32 (0.14, 0.50); p = 003