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. 2020 Aug 27;184(2):311–324. doi: 10.1007/s10549-020-05865-2

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© The Author(s) 2020

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Fig. 1 — Illustration of FGFR1 fluorescence in situ hybridization (FISH). Tumor nuclei are marked using DAPI, the FGFR1 gene is depicted as green signal, the centromere (CEN8) is labeled with an orange signal (×1000, oil). One breast cancer case harbors FGFR1 amplification, whereas the other breast tumor shows normal gene copy number of FGFR1, respectively