Table 2.
Univariable analysis of association between different factors and pCR (n = 124)
| Odds ratio (OR) | 95% Confidence interval (CI) | p value | |
|---|---|---|---|
| Age, years | |||
| ≥ 40 | Ref. | ||
| < 40 | 0.49 | 0.20–1.17 | 0.11 |
| BMI, kg/m2 | |||
| < 25 | Ref. | ||
| ≥ 25 | 0.37 | 0.17–0.83 | 0.015 |
| As continuous variable | 0.93 | 0.87–0.99 | 0.033 |
| ER status | |||
| Negative | Ref. | ||
| Positive | 0.37 | 0.16–0.87 | 0.022 |
| Tumour size, mm | |||
| 0–20 | 3.72 | 0.78–17.75 | 0.099 |
| 21–50 | Ref. | ||
| ≥ 50 | 0.88 | 0.37–2.08 | 0.77 |
| Nodal status | |||
| cN0 | Ref. | ||
| cN+ | 1.06 | 0.51–2.21 | 0.88 |
| dAUC | |||
| ≥ 5.75 | Ref. | ||
| < 5.75 | 0.46 | 0.22–0.97 | 0.042 |
| As continuous variable | 1.73 | 0.99–3.03 | 0.056 |
BMI body mass index, pCR pathological complete response, dAUC, delivered area under the curve, ER, oestrogen receptor